Studies marked with an asterisk (*) are sponsored by NVI and are non-interventional.
| Study Name | Location |
|---|---|
| An in vivo ex vivo study to explore the correlation between amyloid beta plaque identified by fluorescence imaging using the RetiaTM retinal imaging system compared with retinal pathology* | Wills Eye Hosp, Phil. PA Cedars-Sinai Med Ctr |
| A Prospective in vivo Imaging and Retrospective Biopsy Study to Explore the Correlation between Aβ Plaques in the Retina, Identified by Autofluorescence Imaging, and Aβ Plaques Identified in Brain Biopsy Specimens in Patients with Idiopathic Normal Pressure Hydrocephalus (iNPH)* | Kuopio University, Finland and Rush Univ. |
| An In Vivo and Post Mortem Substudy to Explore the Correlation between Aβ Plaques in the Retina, Identified by Autofluorescence Imaging, and Aβ Plaques Identified in Brain and Retinal Pathology* | Rush Univ Med Center, Chicago, IL (up to 4 sites) |
| Cognitive Health in Ageing Register: Investigational, Observational, and Trial Studies in Dementia Research (CHARIOT): Prospective Readiness cohort Study (PRO) ClinicalTrials.gov Identifier: NCT02114372 | Imperial College London Edinburgh University |
| A Cross-Sectional study to explore the correlation between PET SUVR and Aβ plaques in the retina, identified by fluorescence imaging using the Eidon (Retia)TM retinal imaging system with and without curcumin labeling.* | CSIRO Perth & Melbourne, AU |
| Candesartan’s Effects on Alzheimer’s Disease and Related Biomarkers ClinicalTrials.gov Identifier: NCT02646982 | Emory University |
| Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4 Study) ClinicalTrials.gov Identifier: NCT02008357 | UCSD, Emory, Butler, Yale and U. Kentucky |
| Evaluation of Retinal Autofluorescence Imaging to predict Amyloid Status as Determined by PET in Normal, MCI and Early AD Subjects | University of Kentucky Lexington, Kentucky |
| Evaluation of Retinal Autofluorescence Imaging to predict Amyloid Status as Determined by PET in Normal, MCI and Early AD Subjects | Indiana University Bloomington, Indiana |
| Deep and Frequent Phenotyping; Combinatorial Biomarkers for Dementia Experimental Medicine | Oxford University Cambridge University Imperial College London Edinburgh University Manchester Royal Eye Newcastle University University of Exeter |
| A Cross-Sectional Methodology Study of Novel Digital Measures of Cognition in Early Alzheimer’s disease. | Iceland |
| A pilot study to evaluate the ability to detect Aβ plaques utilizing a retinal imaging system and curcumin labeling in patients with Alzheimer’s disease (AD).25 | Sutter Hospital Sacramento, CA |