Investigations

Investigations

Studies marked with an asterisk (*) are sponsored by NVI and are non-interventional.
Study NameLocation
An in vivo ex vivo study to explore the correlation between amyloid beta plaque identified by fluorescence imaging using the RetiaTM retinal imaging system compared with retinal pathology*Wills Eye Hosp, Phil. PA
Cedars-Sinai Med Ctr
A Prospective in vivo Imaging and Retrospective Biopsy Study to Explore the Correlation between Aβ Plaques in the Retina, Identified by Autofluorescence Imaging, and Aβ Plaques Identified in Brain Biopsy Specimens in Patients with Idiopathic Normal Pressure Hydrocephalus (iNPH)*Kuopio University, Finland and Rush Univ.
An In Vivo and Post Mortem Substudy to Explore the Correlation between Aβ Plaques in the Retina, Identified by Autofluorescence Imaging, and Aβ Plaques Identified in Brain and Retinal Pathology*Rush Univ Med Center, Chicago, IL (up to 4 sites)
Cognitive Health in Ageing Register: Investigational, Observational, and Trial Studies in Dementia Research (CHARIOT): Prospective Readiness cohort Study (PRO)
ClinicalTrials.gov Identifier: NCT02114372
Imperial College London
Edinburgh University
A Cross-Sectional study to explore the correlation between PET SUVR and Aβ plaques in the retina, identified by fluorescence imaging using the Eidon (Retia)TM retinal imaging system with and without curcumin labeling.*CSIRO Perth & Melbourne, AU
Candesartan’s Effects on Alzheimer’s Disease and Related Biomarkers
ClinicalTrials.gov Identifier: NCT02646982
Emory University
Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4 Study)
ClinicalTrials.gov Identifier: NCT02008357
UCSD, Emory, Butler, Yale and U. Kentucky
Evaluation of Retinal Autofluorescence Imaging to predict Amyloid Status as Determined by PET in Normal, MCI and Early AD SubjectsUniversity of Kentucky
Lexington, Kentucky
Evaluation of Retinal Autofluorescence Imaging to predict Amyloid Status as Determined by PET in Normal, MCI and Early AD SubjectsIndiana University
Bloomington, Indiana
Evaluation of Retinal Autofluorescence Imaging to predict Amyloid Status as Determined by PET in Normal, MCI and Early AD Subjects*Butler Hospital Providence, Rhode Island
Deep and Frequent Phenotyping; Combinatorial Biomarkers for Dementia Experimental MedicineOxford University
Cambridge University
Imperial College London
Edinburgh University
Manchester Royal Eye
Newcastle University
University of Exeter
A Cross-Sectional Methodology Study of Novel Digital Measures of Cognition in Early Alzheimer’s disease.Iceland
A pilot study to evaluate the ability to detect Aβ plaques utilizing a retinal imaging system and curcumin labeling in patients with Alzheimer’s disease (AD)27
ClinicalTrials.gov Identifier: NCT03319810
Sutter Hospital Sacramento, CA